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11th World Conference on Separation Techniques & Formulation Reports, will be organized around the theme “Exploring the Scientific and Industrial Advancements in Seperation Techniques and Formulation reports”
Separation Techniques 2021 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Separation Techniques 2021
Submit your abstract to any of the mentioned tracks.
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The process of separation is an integral unit operation in most of the Modern Pharmaceutical Techniques, chemical and other process plants. Among the separation processes, some are standard and conventional processes, like, distillation Process, adsorption process, etc. These processes are quite common and the relevant technologies are well developed and well-studied. On the other hand, newer separation processes like, membrane based techniques, super critical fluid extraction, chromatographic separation, etc., are gaining importance in modern days.
- Track 1-1• Advancements in sample preparation techniques
- Track 1-2• Separation techniques
- Track 1-3• chemical engineering methods of isolation and purification
- Track 1-4• Cloud point extraction and mi cellar enhanced separation
- Track 1-5• Decantation
There is a broad growing worldwide interest in step change Separation Technologies, in key areas of physical sorption, distillation process, membranes, absorption and heat exchange. Many of the innovative research activities are initiated by growing concern with environment (e.g. Co2 capture), equipment and energy cost, a number of new technologies find applications in neighbouring processes. This new technology includes ion-pair-reverse liquid chromatography, Multi-dimensional Separations in 3D-printed devices, Industrial membrane filtration technology, Magnetic Separation Techniques in various fields, Cell Separation Techniques in microbiology, super-critical fluid chromatography(SFC), Hydrophilic interaction chromatography (HILIC), Multidimensional Gc separation’s.
- Track 2-1• Membrane technologies for gas separation
- Track 2-2• Mechanical separation.
- Track 2-3• Solid phase extraction chromatography
- Track 2-4• Magnetic separation techniques
- Track 2-5• Super-critical fluid chromatography
- Track 2-6• Industrial membrane separation technology
- Track 2-7• Cell separation techniques in microbiology
Most of the materials in our surroundings are mixture of two or more components. Mixtures are either heterogeneous or homogeneous. Homogeneous mixtures are uniform in composition, but Heterogeneous mixtures are not uniform in composition. The choice of Separation Techniques is based on the mixture type and difference in the chemical properties of the constituents in mixture. This track includes all the basic Separation Techniques like crystallization, distillation, centrifugation, filtration and other methods along with their advancements.
- Track 3-1• Distillation
- Track 3-2• Floatation
- Track 3-3• Chromatography
- Track 3-4• Magnetism
- Track 3-5• Filtration
- Track 3-6• Extraction
- Track 3-7• Crystallization
- Track 3-8• Mechanical Separation
Separation processes—or processes that use physical, chemical, or electrical forces to isolate or concentrate selected constituents of a mixture—are essential to the chemical, petroleum refining, and materials processing industries.
The traditional chemical engineering methods of separation and purification include distillation, crystallization, adsorption, membrane processes, absorption and stripping, and extraction.
- Track 4-1• Field flow Fractionation
- Track 4-2• Electrostatic Separation
- Track 4-3• cyclonic separation
- Track 4-4• Decantation
- Track 5-1• spectroscopic techniques
- Track 5-2• Raman light scattering technique.
- Track 5-3• modern laser techniques
- Track 5-4• separation of mixtures
- Track 5-5• Spectroscopy in biomedical Sciences
The primary goal of sample preparation is to isolate one or several target analytes from the other components of the sample mixture (matrix). Depending on their nature and concentration levels, co-components of the sample matrix can influence the quantitation of target analyte(s) during subsequent liquid chromatography-mass spectrometry (LC-MS) or tandem mass spectrometry (LC-MS/MS) experiments if not removed prior to analysis. The development of new LC-MS/MS methods for small molecules in biological fluids is becoming increasingly more challenging, because of the need to continuously achieve higher sensitivity and better assay robustness in complex bio fluids such as serum, plasma, urine, oral fluid or cerebrospinal fluid (CSF). In addition, because of the very low concentration levels of pharmaceutical targets, samples often need to be pre-concentrated before analysis.
- Track 6-1• microwave sample preparation
- Track 6-2• flow injection analysis
Separation Techniques are the part of separation science where separation of various mixtures is done. Mixtures come in many forms and phases. Most of them can be separated, and the kind of separation method depends on what kind of mixture it is. Thus, these Separation Techniques gain importance in different kinds of industries, different fields like Petroleum Industry,biotechnology, biochemical processes, forensic science, pharmaceutical industry, chemical industry.
- Track 7-1• Separation techniques in waste water treatment
- Track 7-2• Separation techniques in forensic science
- Track 7-3• New separation chemistry techniques for radioactive waste
- Track 7-4• Separation techniques in petroleum industry
In food industry, separation technology is broadly used to separate, isolate, and purify a particular component from a mixture. These are essential in the food manufacturing process. A numerous separation technologies are available such as using membrane, centrifuge, decanter, spray dryer, freeze dryer, and extractor. Especially, membrane technology has been broadly used in the food industry since 5-6 decades due to their processing at a lower temperature and less energy-intensive.
Typically, Microfiltration (MF), Ultrafiltration (UF), Nano filtration (NF), and Reverse Osmosis (RO) are commonly used pressure-driven membrane separation in the food processing. These types differ in membrane characteristics, pore size, and operating pressure. The major membrane applications in the food are dairy and beverage industries. Microfiltration widely used to remove bacteria and spore, fat, and casein from skim milk. Ultrafiltration is used to remove lactose, and increase or decrease the protein content. Nano filtration is used to concentrate and partially demineralize liquid products. Reverse osmosis is mainly used to remove water from a mixture which increase the product concentration with dehydration. Despite the many advantages of membrane technology, it has the key disadvantage which is the fouling of the membrane? It causes a reduction in flux rate and thus decreasing productivity over time. Back flux and chemical cleaning process can be applied to minimize the fouling but not perfect. Advanced technology such as grafted coating, zeolite, and graphene can be applied to solve the fouling issues.
- Track 8-1• Applications of Chromatographic Separation Techniques in Food and Chemistry
- Track 8-2• Optimizing the separation of food dyes by capillary electrophoresis
- Track 8-3• pressure-driven membrane separation in the food processing.
- Track 8-4• Microfiltration
- Track 8-5• Nano filtration
Crystallographic methods now depend on analysis of the diffraction patterns of a sample targeted by a beam of some type. X-rays are most commonly used; other beams used include electrons or neutrons. Crystallographers often explicitly state the type of beam used, as in the terms X-ray crystallography, neutron diffraction and electron diffraction. These three types of radiation interact with the specimen in different ways.
- Track 9-1• first law of crystallography
- Track 9-2• Modern crystallography
- Track 9-3• Crystal Growth in geology
- Track 9-4• neutron diffraction
High Performance Liquid Chromatography (HPLC) is a part of Separation Techniques. It was formerly referred as high-pressure liquid chromatography, as a technique in analytical chemistry used to identify, separate, & quantify each component in mixture. It relies on pumps to pass the pressurized liquid solvent that contains the sample mixture through a column filled with solid adsorbent materials. Each component in the sample interacts slight differently with adsorbent material, thus cause different flow rates for the different components and lead to the separation of the components as they flow out the column. HPLC depends on pumps to pass pressurized liquid & sample mixture through column filled with a sorbent, leading to sample components separation.
- Track 10-1• Separation of Hydroxybenzoic acids
- Track 10-2• Separation and determination of Opium Alkaloids
- Track 10-3• HPLC Operation
- Track 10-4• Chromatogram
Bioanalysis may be a sub-discipline of analytical chemistry covering the quantitative activity of xenobiotic (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and biotic (macro and micro molecules, proteins, DNA, giant molecule medicine, metabolites) in biological systems. Applications for analytical and Bioanalytical method development and validation, are as follows: biological safety test, clinical support, separation of mixture of compound, drug analysis. Importance of understanding proteomics and process of food science is important, and can be discussed by using separation techniques.
- Track 11-1• Analytical proteomics
- Track 11-2• Miniaturized device development
- Track 11-3• Devices for single-cell analysis
Analytical techniques modify researchers to look at complicated relationships between variables and those techniques are Regression Analysis, Grouping ways, Multiple Equation Models. Chemistry that involves the study of the molecular mechanisms underlying the performance of the system, particularly the character of antibodies, antigens and their interactions. The foremost common diagnostic ways include: diagnostic assay, Endoscopy, Diagnostic Imaging, Blood Tests, immunochemical assay. The super molecule detected by the bioassay is usually remarked as Associate in Nursing "analyte" and is in several cases a macromolecule. Analytes in biological liquids like body fluid or area unit often measured mistreatment immuno assays for medical and analysis functions.
- Track 12-1• Nucleic acid-based amplification techniques
- Track 12-2• Reverse transcription-PCR (RT-PCR)
- Track 12-3• Real-time PCR
- Track 12-4• Transcription-based amplification methods
Immune chromatographic Assays in addition cited as Lateral Flow Tests or just Strip Tests unit of measurement immunoassays performed on an easy to use strip format. Amount of your real time quantitative PCR is incredibly correct and fewer effortful than current quantitative PCR ways in which. Needs relatively bit of sample, Adequate level of sensitivity, easy manufacture in large scale, Stability of the last word product at temperature (shelf life) , β-D-Glucan as a Diagnostics Adjunct for Invasive fungal Infections: Validation and drug development, and Performance in Patients with Acute Myelogenous blood cancer .
- Track 13-1• Proteome profiler human phospho-kinase array kit
- Track 13-2• Seralite
- Track 13-3• Access 2 immunoassay system
- Track 13-4• PCR
NMR analysis is used in separation of complex l and natural samples. Recent advances in mass chemical analysis area unit facultative improved analysis of endogenous metabolites. Here we have a tendency to discuss many problems relevant to developing High-Performance Liquid Chromatography, electro spray ionization, mass chemical analysis ways for targeted metabolomics (i.e., menstruation of dozens to many specific metabolites).Lab-on-a-chip devices area unit a set of MEMS instruments and infrequently indicated by "Micro Total Analysis Systems" (µTAS) still.
- Track 14-1• Microplate spectrophotometer
- Track 14-2• Small size but excellent unit of gas chromatogram
- Track 14-3• Albumin analyser’s (Albumin Testing)
- Track 14-4• Automated biochemical analyser
Liquid chromatography-mass spectrum analysis may be a key analytical technique that mixes the physical separation capabilities of liquid action with the mass spectrometry analysis capabilities of spectrometry analysis.LC-MS system is employed for fast and mass directed purification of natural-products extracts and new molecular entities necessary to food, pharmaceutical, agrochemical and different industries. LC-MS is sometimes utilized in drug development research at many different stages, impurity identification, quantitative Bioanalysis, and control. FDA has inspired testing of current quality testing of traditional medicines among medicine patients throughout drug development. Traditional Chinese Medicine is a healing system developed in China more than 2,200 years ago, incorporating therapies that are in some cases. One of its guiding principles is to dispel evil and support the good. In addition to treating illness, Traditional Chinese Medicine focuses on strengthening the body's defences and enhancing its capacity for healing herbs and to maintain health.
- Track 15-1• Overview of LC-MS bioanalysis related regulations
- Track 15-2• Spectrometry analysis.
- Track 15-3• Potency assays
In bioscience and drugs, to a small degree molecule may be a coffee mass (<900 Daltons ) compound which is able to facilitate regulate a process, with a size on the order of 10−9 m. Most drug analysis square measure very little molecules. For analysis of small organic molecules, the subsequent devices ought to be used are as follows HPLC method, chromatography, Ultraviolet-visible (UV-VIS) spectrophotometry, Infrared (IR) spectrometry and mass spectrometry.
- Track 16-1• Configuration determination.
- Track 16-2• ISiCLE calculates the NMR chemical shifts
- Track 16-3• DFT theory
HPLC is a popular method of analysis for natural products because of its high accuracy, precision and is not differed by the stability or the volatility of the compounds. HPLC combined with diode array detector (HPLC-DAD), mass spectrometer (HPLC-MS) have been successfully utilized for the qualitative and quantitative determination of various types of phyto-constituents like alkaloids, glycosides, tannins, tri-terpenes, flavonoids etc. HPLC methods are used readily for the determination of drug in biological fluids and pharmaceutical dosage forms. HPLC determination with spectroscopic detection is useful for routine quality control of drugs in pharmaceutical dosage forms and stability studies.
- Track 17-1• Mass spectrometer (HPLC-MS)
- Track 17-2• Capillary gas chromatography
- Track 17-3• Hydrophilic interaction liquid chromatography
HPLC can be used in both qualitative and quantitative applications that are for both compound quantification and identification. Normal phase HPLC is rarely used now, almost all HPLC separation can be performed in reverse phase. Reverse phase HPLC (RPLC) is ineffective in for only a few separation types. HPLC is applied for molecular weight determination, in analytical chemistry, pharmaceutical and drug science, clinical sciences, food technology, and consumer products, combinatorial chemistry, polymer chemistry, environmental chemistry and green chemistry.
- Track 18-1• Advances in isolation, enrichment and separation
- Track 18-2Lipidomics, metabolomics and ultra-trace analysis
- Track 18-3• Protein phosphorylation and non-covalent interaction
- Track 18-4• Drug metabolism and pharmacokinetics (DMPK)
One of the most characteristic features of the development in the methodology of pharmaceutical and biomedical analysis is that HPLC became undoubtedly the most important analytical method for identification and quantification of drugs, either in their active pharmaceutical ingredient or in their formulations during the process of their discovery, development and manufacturing. Drug development starts with the discovery of a molecule with a therapeutic value. This can be done by high throughput screening during which separations by fast or ultra-fast HPLC are performed. At the discovery stage there can be also characterizing synthetic or natural products. Drug metabolism and pharmacokinetics (DMPK) is the step where the candidate compounds for drug are tested for their metabolism and pharmacokinetics. The studies involve use of LC-MS or LC-MS/MS. The goal in the discovery stage of drug development is to discover a new, safe and active chemical entity (NCE) that will become medication for diseases. During the last decade parallel synthesis of potential lead compounds, using combinatorial chemistry has been done. Due to its high sensitivity and selectivity, HPLC coupled with tandem mass spectrometry, HPLC-MS/MS has become the predominant method in bioassays, and pharmacokinetic and metabolic studies.
- Track 19-1• HPLC coupled with tandem mass spectrometry
- Track 19-2• Metabolic studies.
The analysed samples are subjected to sequencing studies either manually or using different software’s. This is studied as Data mining and sequence analysis. HPLC is also used for characterization of various metabolites.
- Track 20-1• Immunoinformatics
- Track 20-2• HPLC fingerprinting
- Track 20-3• Biochemical applications of chromatography-HPLC